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Development of a Calcium-Sensitive MRI Probe for Neural Activity

PI: Wang

Summary:
Collaborating with Meade, Csernansky, Thulborn (UIC), we demonstrate the feasibility of using MRI and contrast agents to quantify neural activity as reflected by changes in tissue Ca2+ concentration. The experimental methods and data collected from this project will be applied to future studies of intracellular Ca2+ contrast agents.

Funding:

• Brain Research Foundation: Development of a Calcium-Sensitive MRI Probe for Neural Activity (PI: Wang) - We demonstrate the feasibility of using MRI and contrast agents to quantify neural activity as reflected by changes in tissue Ca2+ concentration. The experimental methods and data collected from this project will be applied to future studies of intracellular Ca2+ contrast agents. (05/03/2010 - 05/02/2011).